Intended for healthcare professionals

Rapid response to:


Vaccinating the UK against covid-19

BMJ 2020; 371 doi: (Published 30 November 2020) Cite this as: BMJ 2020;371:m4654

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Rapid Response:

PEG in the Pfizer vaccine: not a good start

Dear Editor

The day after the roll out of the Pfizer vaccine commenced the MHRA were forced to issue a belated warning about the risk of anaphylaxis with particular suspicion surrounding the ingredient Polyetheline Glycol (PEG). MHRA Chief Executive June Raine said in a statement:

“Any person with a history of anaphylaxis to a vaccine, medicine or food should not receive the Pfizer BioNTech vaccine”

It was indicated that the issue may not come to light because people susceptible to allergic reactions had been excluded from Pfizer’s trials in the first place [1].

It is troubling this issue should have been revealed only after the product was offered to the public since it is apparent from the Reuter’s report that it was a known risk. In particular, I would point out that Children’s Health Defense, an organisation with which I am associated, including its chairman Robert F Kennedy Jr, wrote to the US government alerting it to the issue of PEG in relation to the rival Moderna product in August [2,3].

[1] Alistair Smout, ‘ UK issues anaphylaxis warning on Pfizer vaccine after adverse reactions’, Reuters 9 December 2020,

[2] Lyn Redwood, ‘ Breaking: CHD Responds to News of Life-Threatening Reaction to Pfizer COVID Vaccine. Will Regulators Take Action?’, Children’s Health Defense 9 December 2020,

[3] Robert F Kennedy Jr, Lyn Redwood, Harold Gielow, Letter to Dr Jerry Menikoff (Director, Office for Human Research Protections, Department of Health and Human Services), 26 August 2020,

Competing interests:, an on-line daily journal, concerns itself with the potential environmental sources for the proliferation of autism, neurological impairment, immune dysfunction and chronic disease. I receive no payment as UK Editor. I also moderate comments for the on-line journal ‘The Defender’ for which I am paid. I am also a member of the UK Medical Freedom Alliance

10 December 2020
John Stone
UK Editor
London N22