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Treatment effects in randomised trials using routinely collected data for outcome assessment versus traditional trials: meta-research study

March 3, 2021

High flow oxygen and risk of mortality in patients with a suspected acute coronary syndrome: pragmatic, cluster randomised, crossover trial

March 2, 2021

SARS-CoV-2 lateral flow assays for possible use in national covid-19 seroprevalence surveys (React 2): diagnostic accuracy study

March 2, 2021

Instrumental variable meta-analysis of aggregated randomized drug trial data for evaluating proposed target mechanisms

February 25, 2021

Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis

February 25, 2021

Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials

February 24, 2021

Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years: prospective, cluster randomised controlled trial in Mumbai

February 24, 2021

Excess mortality in Wuhan city and other parts of China during the three months of the covid-19 outbreak: findings from nationwide mortality registries

February 24, 2021

Covid-19 deaths in Africa: prospective systematic postmortem surveillance study

February 17, 2021

Food anaphylaxis in the United Kingdom: analysis of national data, 1998-2018

February 17, 2021

Use of SNP chips to detect rare pathogenic variants: retrospective, population based diagnostic evaluation

February 15, 2021

Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study

February 11, 2021

Association of first trimester prescription opioid use with congenital malformations in the offspring: population based cohort study

February 10, 2021

Association between use of macrolides in pregnancy and risk of major birth defects: nationwide, register based cohort study

February 10, 2021

Association between antihypertensive treatment and adverse events: systematic review and meta-analysis

February 10, 2021

Prospective validation of Canadian TIA Score and comparison with ABCD2 and ABCD2i for subsequent stroke risk after transient ischaemic attack: multicentre prospective cohort study

February 4, 2021

Use of high dose cyproterone acetate and risk of intracranial meningioma in women: cohort study

February 3, 2021

Associations of cereal grains intake with cardiovascular disease and mortality across 21 countries in Prospective Urban and Rural Epidemiology study: prospective cohort study

February 3, 2021

Update to living systematic review on prediction models for diagnosis and prognosis of covid-19

February 3, 2021

Effect of redundant clinical trials from mainland China evaluating statins in patients with coronary artery disease: cross sectional study

February 2, 2021

Association between human papillomavirus vaccination and serious adverse events in South Korean adolescent girls: nationwide cohort study

January 29, 2021

Association between county level cannabis dispensary counts and opioid related mortality rates in the United States: panel data study

January 27, 2021

Efficacy and safety of antidepressants for the treatment of back pain and osteoarthritis: systematic review and meta-analysis

January 20, 2021

Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial

January 20, 2021

Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial

January 19, 2021

Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial

January 18, 2021

Efficacy and safety of low and very low carbohydrate diets for type 2 diabetes remission: systematic review and meta-analysis of published and unpublished randomized trial data

January 13, 2021

Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials

January 13, 2021

Use of proton pump inhibitors to treat persistent throat symptoms: multicentre, double blind, randomised, placebo controlled trial

January 7, 2021

Association between home insulation and hospital admission rates: retrospective cohort study using linked data from a national intervention programme

December 29, 2020

Update to living systematic review on drug treatments for covid-19

December 17, 2020

Does medicine run in the family—evidence from three generations of physicians in Sweden: retrospective observational study

December 16, 2020

Association of high profile football matches in Europe with traffic accidents in Asia: archival study

December 16, 2020

Effectiveness of hospital clowns for symptom management in paediatrics: systematic review of randomised and non-randomised controlled trials

December 16, 2020

Estimating my equilibrium energy intake during lockdown: very introspective study

December 16, 2020

Comparative evaluation of clinical manifestations and risk of death in patients admitted to hospital with covid-19 and seasonal influenza: cohort study

December 15, 2020

Global, regional, and national estimates of target population sizes for covid-19 vaccination: descriptive study

December 15, 2020

Reserving coronavirus disease 2019 vaccines for global access: cross sectional analysis

December 15, 2020

Nonsensus in the treatment of proximal humerus fractures: uncontrolled, blinded, comparative behavioural analysis between Homo chirurgicus accidentus and Macaca sylvanus

December 14, 2020

Effect of therapeutic suggestions during general anaesthesia on postoperative pain and opioid use: multicentre randomised controlled trial

December 10, 2020

The shared risk of diabetes between dog and cat owners and their pets: register based cohort study

December 10, 2020

Toxicological analysis of George’s marvellous medicine: literature review

December 10, 2020

Patient mortality after surgery on the surgeon’s birthday: observational study

December 10, 2020

The Babinski sign in Renaissance paintings—a reappraisal of the toe phenomenon in representations of the Christ Child: observational analysis

December 10, 2020

The time to act is now: pseudo-systematic review

December 10, 2020

Association between conflicts of interest and favourable recommendations in clinical guidelines, advisory committee reports, opinion pieces, and narrative reviews: systematic review

December 9, 2020

Association between low density lipoprotein and all cause and cause specific mortality in Denmark: prospective cohort study

December 8, 2020

Red meat intake and risk of coronary heart disease among US men: prospective cohort study

December 2, 2020

Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults

December 2, 2020

Clinical spectrum of coronavirus disease 2019 in Iceland: population based cohort study

December 2, 2020

Active conventional treatment and three different biological treatments in early rheumatoid arthritis: phase IV investigator initiated, randomised, observer blinded clinical trial

December 2, 2020

Infection fatality risk for SARS-CoV-2 in community dwelling population of Spain: nationwide seroepidemiological study

November 27, 2020

Gestational age and hospital admissions during childhood: population based, record linkage study in England (TIGAR study)

November 25, 2020

Association between neuraxial anaesthesia or general anaesthesia for lower limb revascularisation surgery in adults and clinical outcomes: population based comparative effectiveness study

November 25, 2020

Treatment interventions to maintain abstinence from alcohol in primary care: systematic review and network meta-analysis

November 25, 2020

First line drug treatment for hypertension and reductions in blood pressure according to age and ethnicity: cohort study in UK primary care

November 18, 2020

Pregravid contraceptive use and fecundability: prospective cohort study

November 11, 2020

Accuracy of UK Rapid Test Consortium (UK-RTC) “AbC-19 Rapid Test” for detection of previous SARS-CoV-2 infection in key workers: test accuracy study

November 11, 2020

Accuracy of the Edinburgh Postnatal Depression Scale (EPDS) for screening to detect major depression among pregnant and postpartum women: systematic review and meta-analysis of individual participant data

November 11, 2020

Consistency of variety of machine learning and statistical models in predicting clinical risks of individual patients: longitudinal cohort study using cardiovascular disease as exemplar

November 4, 2020

Mortality due to cancer treatment delay: systematic review and meta-analysis

November 4, 2020

Associations between high temperatures in pregnancy and risk of preterm birth, low birth weight, and stillbirths: systematic review and meta-analysis

November 4, 2020

Effect of monitoring surgical outcomes using control charts to reduce major adverse events in patients: cluster randomised trial

November 4, 2020

Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases

October 28, 2020

Risk of hospital admission with coronavirus disease 2019 in healthcare workers and their households: nationwide linkage cohort study

October 28, 2020

Influence and management of conflicts of interest in randomised clinical trials: qualitative interview study

October 27, 2020

Autocratisation and universal health coverage: synthetic control study

October 23, 2020

Convalescent plasma in the management of moderate covid-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial)

October 22, 2020

Regulatory T cells for minimising immune suppression in kidney transplantation: phase I/IIa clinical trial

October 21, 2020

Living risk prediction algorithm (QCOVID) for risk of hospital admission and mortality from coronavirus 19 in adults: national derivation and validation cohort study

October 20, 2020

Effectiveness of pelvic floor muscle training with and without electromyographic biofeedback for urinary incontinence in women: multicentre randomised controlled trial

October 14, 2020

Incentive programmes for smoking cessation: cluster randomized trial in workplaces in Thailand

October 14, 2020

Targeting rehabilitation to improve outcomes after total knee arthroplasty in patients at risk of poor outcomes: randomised controlled trial

October 13, 2020

Effect of school closures on mortality from coronavirus disease 2019: old and new predictions

October 7, 2020

Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review

October 7, 2020

Association between FDA and EMA expedited approval programs and therapeutic value of new medicines: retrospective cohort study

October 7, 2020

Effect of exercise training for five years on all cause mortality in older adults—the Generation 100 study: randomised controlled trial

October 7, 2020

Fifteen year quality of life outcomes in men with localised prostate cancer: population based Australian prospective study

October 7, 2020

Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study

October 1, 2020

Menstrual cycle regularity and length across the reproductive lifespan and risk of premature mortality: prospective cohort study

September 30, 2020

In-hospital cardiac arrest in critically ill patients with covid-19: multicenter cohort study

September 30, 2020

Sodium glucose cotransporter 2 inhibitors and risk of major adverse cardiovascular events: multi-database retrospective cohort study

September 23, 2020

Central fatness and risk of all cause mortality: systematic review and dose-response meta-analysis of 72 prospective cohort studies

September 23, 2020

Computerised clinical decision support systems and absolute improvements in care: meta-analysis of controlled clinical trials

September 17, 2020

Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries

September 16, 2020

Opportunistic screening versus usual care for detection of atrial fibrillation in primary care: cluster randomised controlled trial

September 16, 2020

Update to living systematic review on drug treatments for covid-19

September 11, 2020

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

September 9, 2020

Association between high blood pressure and long term cardiovascular events in young adults: systematic review and meta-analysis

September 9, 2020

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