Research Articles

Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study

Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial

Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study

Benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery: systematic review and network meta-analysis of randomised trials

Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis

Survival for waitlisted kidney failure patients receiving transplantation versus remaining on waiting list: systematic review and meta-analysis

The effects of plasma exchange in patients with ANCA-associated vasculitis: an updated systematic review and meta-analysis

SARS-CoV-2 antigen lateral flow tests for detecting infectious people: linked data analysis

Effectiveness of physical activity interventions delivered or prompted by health professionals in primary care settings: systematic review and meta-analysis of randomised controlled trials

Full endoscopic versus open discectomy for sciatica: randomised controlled non-inferiority trial

Early identification of patients admitted to hospital for covid-19 at risk of clinical deterioration: model development and multisite external validation study

Risks of mental health outcomes in people with covid-19: cohort study

Mortality among US veterans after emergency visits to Veterans Affairs and other hospitals: retrospective cohort study

Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study

Interventions to prevent spontaneous preterm birth in women with singleton pregnancy who are at high risk: systematic review and network meta-analysis

Effectiveness of mRNA vaccines and waning of protection against SARS-CoV-2 infection and severe covid-19 during predominant circulation of the delta variant in Italy: retrospective cohort study

App based education programme to reduce salt intake (AppSalt) in schoolchildren and their families in China: parallel, cluster randomised controlled trial

Risk of persistent and new clinical sequelae among adults aged 65 years and older during the post-acute phase of SARS-CoV-2 infection: retrospective cohort study

The prevalence of loneliness across 113 countries: systematic review and meta-analysis

Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial

Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study

Effectiveness of physical activity monitors in adults: systematic review and meta-analysis

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial

Surgical fixation with K-wires versus casting in adults with fracture of distal radius: DRAFFT2 multicentre randomised clinical trial

Drug treatment for panic disorder with or without agoraphobia: systematic review and network meta-analysis of randomised controlled trials

Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies

Healthcare use in 700 000 children and adolescents for six months after covid-19: before and after register based cohort study

Indirect effects of the covid-19 pandemic on childhood infection in England: population based observational study

Atorvastatin versus placebo in patients with covid-19 in intensive care: randomized controlled trial

Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial

GP consultation rates for sequelae after acute covid-19 in patients managed in the community or hospital in the UK: population based study

Evaluation of pathological complete response as surrogate endpoint in neoadjuvant randomised clinical trials of early stage breast cancer: systematic review and meta-analysis

Respiratory tract infection and risk of bleeding in oral anticoagulant users: self-controlled case series

SARS-CoV-2 vaccination and myocarditis or myopericarditis: population based cohort study

Giving science the finger—is the second-to-fourth digit ratio (2D:4D) a biomarker of good luck? A cross sectional study

Heavy metal toxicity and mortality—association between density of heavy metal bands and cause specific hospital admissions and mortality: population based cohort study

Ghost in the machine or monkey with a typewriter—generating titles for Christmas research articles in The BMJ, using artificial intelligence: observational study

Effectiveness of mRNA-1273 against delta, mu, and other emerging variants of SARS-CoV-2: test negative case-control study

Bah humbug! Association between sending Christmas cards to trial participants and trial retention: randomised study within a trial conducted simultaneously across eight host trials

Association of Logic’s hip hop song “1-800-273-8255” with Lifeline calls and suicides in the United States: interrupted time series analysis

“It’s not rocket science” and “It’s not brain surgery”—“It’s a walk in the park”: prospective comparative study

Association of bilateral salpingo-oophorectomy with all cause and cause specific mortality: population based cohort study

Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial

Multifactorial falls prevention programme compared with usual care in UK care homes for older people: multicentre cluster randomised controlled trial with economic evaluation

Financial incentives for smoking cessation in pregnancy: multicentre randomised controlled trial

Timing of dialysis initiation to reduce mortality and cardiovascular events in advanced chronic kidney disease: nationwide cohort study

Discordant and inappropriate discordant recommendations in consensus and evidence based guidelines: empirical analysis

Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection: test negative design study

Ambient heat and risks of emergency department visits among adults in the United States: time stratified case crossover study

Effect of PEP flute self-care versus usual care in early covid-19: non-drug, open label, randomised controlled trial in a Danish community setting

Prescription opioid treatment for non-cancer pain and initiation of injection drug use: large retrospective cohort study

Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis

Sex differences in mortality among binational cohort of people with chronic kidney disease: population based data linkage study

Exercise versus usual care after non-reconstructive breast cancer surgery (UK PROSPER): multicentre randomised controlled trial and economic evaluation

Effect of nutritionally modified infant formula on academic performance: linkage of seven dormant randomised controlled trials to national education data

Epinephrine before defibrillation in patients with shockable in-hospital cardiac arrest: propensity matched analysis

Use of whole genome sequencing to determine genetic basis of suspected mitochondrial disorders: cohort study

Mapping conflict of interests: scoping review

Effects of covid-19 pandemic on life expectancy and premature mortality in 2020: time series analysis in 37 countries

Inhaled and intranasal ciclesonide for the treatment of covid-19 in adult outpatients: CONTAIN phase II randomised controlled trial

Cardioversion in patients with newly diagnosed non-valvular atrial fibrillation: observational study using prospectively collected registry data

Effect of dietary sources of calcium and protein on hip fractures and falls in older adults in residential care: cluster randomised controlled trial

Risk of bias in studies on prediction models developed using supervised machine learning techniques: systematic review

Acute urinary retention and risk of cancer: population based Danish cohort study

Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial

Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies

Conduct and reporting of formula milk trials: systematic review

Current evidence on dietary intakes of fatty acids and mortality

Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network meta-analysis

Changes in exposure to ambient fine particulate matter after relocating and long term survival in Canada: quasi-experimental study

Female authorship of covid-19 research in manuscripts submitted to 11 biomedical journals: cross sectional study

Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression: updated systematic review and individual participant data meta-analysis

Post-discharge after surgery Virtual Care with Remote Automated Monitoring-1 (PVC-RAM-1) technology versus standard care: randomised controlled trial

Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases

Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial

Performance of prediction models for nephropathy in people with type 2 diabetes: systematic review and external validation study

Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis

Use of metformin to prolong gestation in preterm pre-eclampsia: randomised, double blind, placebo controlled trial

Effect of C reactive protein point-of-care testing on antibiotic prescribing for lower respiratory tract infections in nursing home residents: cluster randomised controlled trial

Procalcitonin and lung ultrasonography point-of-care testing to determine antibiotic prescription in patients with lower respiratory tract infection in primary care: pragmatic cluster randomised trial

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study

Evaluating agreement between bodies of evidence from randomised controlled trials and cohort studies in nutrition research: meta-epidemiological study

Use of antipsychotic drugs and cholinesterase inhibitors and risk of falls and fractures: self-controlled case series

Residential exposure to transportation noise in Denmark and incidence of dementia: national cohort study

Regulatory and clinical consequences of negative confirmatory trials of accelerated approval cancer drugs: retrospective observational study

Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials

Long term exposure to low level air pollution and mortality in eight European cohorts within the ELAPSE project: pooled analysis

Risk of hospital admission with covid-19 among teachers compared with healthcare workers and other adults of working age in Scotland, March 2020 to July 2021: population based case-control study

Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy

Risk of thrombocytopenia and thromboembolism after covid-19 vaccination and SARS-CoV-2 positive testing: self-controlled case series study

Effectiveness of BNT162b2 and mRNA-1273 covid-19 vaccines against symptomatic SARS-CoV-2 infection and severe covid-19 outcomes in Ontario, Canada: test negative design study

Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study

Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies

Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study

Association between characteristics of behavioural weight loss programmes and weight change after programme end: systematic review and meta-analysis