Intended for healthcare professionals

Rapid response to:

Clinical Review

Investigation and management of uveitis

BMJ 2010; 341 doi: (Published 13 October 2010) Cite this as: BMJ 2010;341:c4976

Rapid Response:

Cycloplegics in Uveitis

Cycloplegics are also very important to stabilize and restore the
blood-aqueous barrier, thus reducing the amount of inflammatory cell and
flare (proteins leakage) reaction in the anterior chamber in uveitis.
The important complication of cycloplegic use is the potential for
inducing acute angle-closure glaucoma, a true ocular emergency with acute
severe and potentially permanent sight loss, from the pupil dilating
effect of these agents. A shallow anterior chamber is a risk factor that
should be evaluated with slit lamp exam before inducing mydriasis and/or
cycloplegia. The risk of precipitating an attack after evaluation should
be minimal.

Competing interests: No competing interests

27 December 2010
Erkan Mutlukan MD PhD
Eye Specialist UK Ltd