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Research

Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis

BMJ 2011; 342 doi: https://doi.org/10.1136/bmj.d671 (Published 22 February 2011) Cite this as: BMJ 2011;342:d671

Rapid Response:

Alcohol Consumption and Stroke

This is very interesting article. Previous studies on the
relationship between alcohol consumption and stroke have shown
inconsistent results. There is evidence of an association between heavy
drinking and stroke, and a positive dose-response relationship has been
found between alcohol intake and hemorrhagic stroke.Alcohol in excess
(more than 2 drinks a day) can contribute to hypertension that we all know
contributes directly to stroke.There is also evidence that alcohol can
inhibit coagulation and this might explain why alcohol tends to directly
relate to hemorrhagic stroke. This same coagulation effect seems to
protect against ischemic strokes. Light or moderate alcohol consumption
has been attributed to reduced clotting of thrombocytes and reduced
fibrinogen concentration, which reduce the risk of formation of thrombi in
blood vessels.

Competing interests: No competing interests

05 March 2011
Rizaldy Pinzon
Neurologist
Bethesda Hospital Yogyakarta Indonesia 55224