Intended for healthcare professionals


How do psychiatric drugs work?

BMJ 2009; 338 doi: (Published 29 May 2009) Cite this as: BMJ 2009;338:b1963

Psychiatric Drugs: Fact or Fiction

Psychiatric drugs ostensibly help patients by correcting imbalances in
neurotransmitters, such as dopamine, serotonin, epinephrine (adrenaline), and
norepinephrine (noradrenaline). Unfortunately, this simple and straightforward
theory doesn’t translate into practical results. Instead, psychiatric drugs tend to
hurt patients by creating new neuropsychiatric problems, which complicate and
aggravate pre-existing psychiatric problems. I suggest that the mechanism of
action for psychiatric drugs is a folie à deux between doctor and
patient, which has been cultivated by Big Pharma, whose economic might
exerts enormous control over medical schools, medical societies, medical
journals, and the media.

Competing interests:
None declared

Competing interests: No competing interests

09 June 2009
Hugh Mann
Eagle Rock, MO 65641 USA