Intended for healthcare professionals

Rapid response to:

Paper

Environmental tobacco smoke and tobacco related mortality in a prospective study of Californians, 1960-98

BMJ 2003; 326 doi: https://doi.org/10.1136/bmj.326.7398.1057 (Published 15 May 2003) Cite this as: BMJ 2003;326:1057

Rapid Response:

Professor Repace has gone quiet

At soccer matches in the UK if it has reached an indistinct phase or
a team is losing a group of supporters often start singing/chanting, "its
all gone quiet over there." Or have the usual suspects asked you to stop
digging the hole?

I have 3 more posts to make but I have just come across this gem that
was published in The Lancet in July 2008 on lung cancer in non smokers, I
would be very grateful for your comments.

"Molecular genetics of lung cancer in people who have never smoked."

"Patients with lung cancer who have never smoked are more likely to
have mutations in epidermal growth factor receptor (EGFR) tyrosine kinase
and have better response to its inhibitors than do patients with tobacco-
associated lung cancer. Furthermore, the prevalences of mutations in KRAS
and P53 differ for patients with lung cancer who have never smoked and
those with tobacco-associated lung cancer. Genetic mutations seem to be
more common in patients with tobacco-associated lung cancer than in never
smokers. CURRENT EVIDENCE INDICATES THAT THE TWO TYPES OF LUNG CANCER ARE
BIOLOGICALLY DISTINCT."

http://www.ncbi.nlm.nih.gov/pubmed/18598932?ordinalpos=1&itool=PPMCLayou...

Competing interests:
Director, Freedom2Choose smokers rights organisation. Do I need to bang on about that I am not funded by pharmaceutical or tobacco comapnies?

Competing interests: No competing interests

18 January 2010
Dave C Atherton
Salesman
EC3A