Paracetamol and Ibuprofen (or Dipyrone) 3 hours each
Family Physicians and Pediatricians in Brazil normally prescribe
Paracetamol plus Dipyrone (that has proved its safety here)or Ibuprofen
only when fever comes up before 6 hours since last dose of one of them.
But they're not used at the same time. We normally use only one, 3
hours each, IF fever comes up before the intervall between the doses of a
single one.
Fever is a normal reaction of the body and the main problem about it
is febrile seizure, that has been proved not to harm (febrile seizure is a
normal reaction of the body and does not impair cognition, neurological
development or any other neurological condition).
So, I agree with the colleagues when they use paracetamol as the
first choice and associate other drugs only in cases they are needed.
3. Martin Richardson, Monica Lakhanpaul and on behalf of the
Guideline. Assessment and initial management of feverish illness in
children younger than 5 years:summary of NICE guidance. BMJ 2007;334;1163-
1164. http://bmj.com/cgi/content/full/334/7604/1163
4. Brazilian Cochrane Centre. Dipyrone for acute primary headaches.
Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004842
Rapid Response:
Paracetamol and Ibuprofen (or Dipyrone) 3 hours each
Family Physicians and Pediatricians in Brazil normally prescribe
Paracetamol plus Dipyrone (that has proved its safety here)or Ibuprofen
only when fever comes up before 6 hours since last dose of one of them.
But they're not used at the same time. We normally use only one, 3
hours each, IF fever comes up before the intervall between the doses of a
single one.
Fever is a normal reaction of the body and the main problem about it
is febrile seizure, that has been proved not to harm (febrile seizure is a
normal reaction of the body and does not impair cognition, neurological
development or any other neurological condition).
So, I agree with the colleagues when they use paracetamol as the
first choice and associate other drugs only in cases they are needed.
1. Febrile Seizures: Clinical Practice Guideline for the Long-term
Management of the Child With Simple Febrile Seizures. Pediatrics
2008;121;1281-1286. http://www.pediatrics.org/cgi/content/full/121/6/1281
2. Anthony Harnden. Editorial: Antipyretic treatment for feverish
young children in primary care. BMJ 2008; 337:a1409.
http://www.bmj.com/cgi/content/extract/337
3. Martin Richardson, Monica Lakhanpaul and on behalf of the
Guideline. Assessment and initial management of feverish illness in
children younger than 5 years:summary of NICE guidance. BMJ 2007;334;1163-
1164. http://bmj.com/cgi/content/full/334/7604/1163
4. Brazilian Cochrane Centre. Dipyrone for acute primary headaches.
Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004842
Competing interests:
None declared
Competing interests: No competing interests