Intended for healthcare professionals

Rapid response to:

Feature Drug marketing

Key opinion leaders: independent experts or drug representatives in disguise?

BMJ 2008; 336 doi: https://doi.org/10.1136/bmj.39575.675787.651 (Published 19 June 2008) Cite this as: BMJ 2008;336:1402

Rapid Response:

KOL and disclosure

I hope that Roy Moynihnan's editorial is part of a chain of awareness of the pharmaceutical industry's use of Key Opinion Leaders (KOL). There are a couple of arguments commonly put forward to defend the KOL practice: the most prominent, seen again in the discussion of these articles, is that disclosure is imperative and mitigates the impact of potential conflict. I don't think that there is any research to support this statement and fear that physicians have become culturally inured to industry-driven CME without critically examining the potential effects of conflict. In other words, it is the perception of conflict that matters not the action of declaring it. Indeed, there is a risk that 'disclosure' allows the audience to justify or feel more comfortable about their attendance at marketing-driven CME events rather than provoking critical evaluation of the material presented. The second argument, that I've heard espoused by KOL themselves , is that their participation in events and receipt of remuneration from several pharma companies is a measure of their neutrality. This is strikingly naive and misses much of the argument against these practices.

The tide may be turning - Pfizer (US) have recently announced that they will henceforth only provide support to accredited CME performed by medical schools and national organizations: this will make it far more palatable for those KOL, like Dr McAllister-Williams, who feel their role all along has been to disseminate evidence and promote excellence in clinical care.

A more subtle, unchecked and dubious use of KOL is the hearsay reporting of their statements by marketing representatives when visiting physicians in the community. Again it may be a matter of education in our medical schools to enhance sensitivity to marketing techniques. Other health professionals also need awareness, especially as nurse practitioners, special clinic nurses and pharmacists assume greater influence in prescription of medications.

Airing this matter will achieve more by improving the sophistication of the target audience than appealing to industry or those who earn significant sums from them.

Competing interests: None declared

Competing interests: No competing interests

04 July 2008
Alun L Edwards
Division of Endocrinology
University of Calgary