Intended for healthcare professionals

Rapid response to:

Endgames Case Report

Life threatening lactic acidosis

BMJ 2010; 340 doi: (Published 25 March 2010) Cite this as: BMJ 2010;340:c857

Rapid Response:

An Irbesartan/Hydrochlorothiazide overdose as well?

Dear editor,

in addition to the overzealous metformin treatment, as noted by Dr
Tauzeeh, this patient was as well prescribed an overdose of irbesartan
(1200mg daily) and hydrochlorothiazide (100mg) - if these dosages are not
due to a printing error (which I hope).
If she really took these doses, this should have contributed to her renal

Competing interests:
None declared

Competing interests: No competing interests

18 April 2010
Hans Koehn
Physician (general internal medicine)
53175 Bonn/Germany