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Rapid response to:


Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database

BMJ 2010; 340 doi: (Published 20 May 2010) Cite this as: BMJ 2010;340:c2197

Rapid Response:

Final nail in the coffin of statins for women in primary prevention?

With the Jupiter trial using statins in the more vulnerable group of
women over 60 showing no reduction in all cause mortality, although
confirming a reduction in cvs mortality, this research quantifies the
negative effects of statins and must surely confirm that statins should
not be prescribed to women in primary prevention. In addition this
research shows significant morbidity including an ability to cause
cataracts greater than the ability to reduce cvs events.

This research is of great interest to psychiatrists who are battling with
the 25 year loss of life of their patients with schizophrenia mostly from
natural causes. We are extremely
sensitive to the concept of first doing no harm.

Mora S, Glynn RJ, Hsia J, MacFadyen JG, Genest J, Ridker PM. Circulation.
2010 Mar 9;121(9):1069-77. Epub 2010 Feb 22

Jari Tiihonen, Jouko Lönnqvist, Kristian Wahlbeck, Timo Klaukka, Leo
Niskanen , Antti Tanskanen , Jari Haukka d.The Lancet, Volume 374, Issue
9690, Pages 620 - 627, 22 August 2009

Competing interests:
I have on occasions given lectures for and received hospitality from Eli Lilly

Competing interests: No competing interests

07 June 2010
Michael D Beary
Consultant Psychiatrist
Priory Hospital North London, Southgate N14 6RA