Predicting risk of osteoporotic fracture in men and women in England and Wales: prospective derivation and validation of QFractureScores

I interestingly read the article of Dr. Hippisley-Cox and Dr.
Coupland. It seems that QFractureScores indeed accurately predicts the
osteoporotic hip fractures in both men and women than FRAX. Up to now,
many triage screening tools that may predict risk of osteoporotic
fractures or identify individuals with low skeletal bone mineral density
have been developed using a lot of large cohorts. However, it still
remains unknown whether these screening tools including QFractureScores
actually could reduce the incidence of osteoporotic fractures in the real
world. Many scores regarding several chronic diseases such as type 2
diabetes, cardiovascular diseases and so on were included to develop
QFractureScores, implying the possibility that both men and women
identified by QFractureScores may not easily receive the medical
interventions because of high probability of less adherence or compliance
for medications. This may result in less prevention of osteoporotic
fractures. It is preferable for us to know how many individuals identified
by QFractureScores receive medical intervention after screening and
whether QFractureScores can actually reduce the incidence of osteoporotic
fractures in the large community. Well-designed randomized control trial
would be necessary to clarify these important problems. Development and
validation of new triage screening tools for osteoporotic fractures are
now enough. Next step would be necessary.

Competing interests:
None declared