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Research

Cerebral emboli as a potential cause of Alzheimer's disease and vascular dementia: casecontrol study

BMJ 2006; 332 doi: https://doi.org/10.1136/bmj.38814.696493.AE (Published 11 May 2006) Cite this as: BMJ 2006;332:1119

Query about medication

I understand that the authors excluded all subjects who were taking
anticoagulants. There is no mention of whether aspirin and antiplatelet
drug takers were also excluded. The results indicate the increased
incidence of spontaneous cerebral embolism in both subjects with
Alzheimer's disease and vascular dementia. However, there was a lower
incidence in the vascular group which suggests that a medication of this
type may have been taken.
Indeed, I would find it hard to locate a group of patients with diagnosed
vascular dementia who were not prescibed some such medication.
Could the authors comment on this.

Competing interests:
None declared

Competing interests: No competing interests

18 May 2006
A.M. Haddow
Consultant in Old Age Psychiatry
Royal Cornhill Hospital AB25 2ZH