Naloxone as a reagent
Naloxone and/or nalorphine are in common use in toxicology
laboratlories as internal standards for chromatographic identification and
quantitation of opiates and other basic drugs. Therapeutic (whether
administered by professional or lay persons) use of naloxone (if known)
should be notified to an investigating laboratory to allow approporiate
changes to be made to analytical methods. Such notification is
particularly important when a rapid analytical response is required (e.g.
in the identification of substances that may obfuscate clinical
examination to determine brain death). Failure to notify will lead to
failure of the analysis through failure of quality assurance checking
procedures thus delaying analysis for entirely avoidable reasons.
Competing interests: No competing interests