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Research

A meta-analysis of the association between adherence to drug therapy and mortality

BMJ 2006; 333 doi: https://doi.org/10.1136/bmj.38875.675486.55 (Published 29 June 2006) Cite this as: BMJ 2006;333:15

Extrapolation of meta-analysis findings.

In the meta-analysis by Simpson et al (1), it showed that there was
positive association between good adherence to drug therapy with positive
health outcomes. Having read the online inclusion criteria for their meta-
analysis, I am perplexed that only studies related to HIV infection,
diabetes and cardiovascular diseases were included into their meta-
analysis.

Does this imply that the findings from the meta-analysis could be
extrapolated to adherence of psychiatric or paediatric drug therapies as
well? Perhaps a more specific concluding statement directed just to the
studies included could have been made.

1)Simpson SH, Eurich DT, Majumdar SR, Padwal R, Tsuyuki RT, Varney J,
Johnson JA: A meta-analysis of the association between adherence to drug
therapy and mortality, BMJ 2006; 333:15

Competing interests:
None declared

Competing interests: No competing interests

05 July 2006
Albert Tan
5th year medical student
University of Dundee, DD1 4HN