Encephalitis lethargica syndrome in London, 2004.
January 2004 the Great Ormond Street Hospital and Institute of Child
Health published a paper on pharyngitis, complicated by sleep disorder,
lethargy, parkinsonism, dyskinesia and neuropsychiatric symptoms.
Autoantibodies reactive against discrete basal ganglia autoantigens
It is therefore possible that Streptococcus may play an aetiological
role in the Encephalitis lethargica phenotype, as it does in Sydenham's
Dale RC, Church AJ, Surtees RA et al.: Encephalitis lethargica
syndrome: 20 new cases and evidence of basal ganglia autoimmunity. Brain
Competing interests: No competing interests