Intended for healthcare professionals

Rapid response to:


Trial protocols: time for more than tinkering

BMJ 2005; 330 doi: (Published 17 February 2005) Cite this as: BMJ 2005;330:421

Rapid Response:

Some benefit surely.

Many wrong conclusions about the effects of treatments are due to
misinterpretation and a lack of understanding rather than to deliberate
fraud. This is surely where availability of the protocol will help in
reviewing reported trial results. As with any scientific experiment, the
most reliable way of ensuring the results are valid is for it to be
reproducible by others, and perhaps this is the only way of being certain
that the results of a particular trial are not deliberately manipulated.

Competing interests:
None declared

Competing interests: No competing interests

18 February 2005
Sue M Richards
Senior research fellow
CTSU, Oxford, OX2 6HE