Intended for healthcare professionals

Primary Care

Penicillin for acute sore throat in children: randomised, double blind trial

BMJ 2003; 327 doi: https://doi.org/10.1136/bmj.327.7427.1324 (Published 04 December 2003) Cite this as: BMJ 2003;327:1324

Regimen used was ineffective in the first place

To the Editors:

I disagree with Zwart et al. in their recommending against the
routine use of antibiotics for streptococcal pharyngitis.
It appears that conclusions were drawn before study was conducted. When I
saw that in their study, even 7 day course of Penicillin was not
successful in eradicating Streptococcus in 38% patients, I was dismayed.
More Straightforward conclusion would be that a more effective antibiotics
regimen is warranted than a 7 day course of Penicillin (as was done after
breaking the code for those with sequelae).
Comparing an ineffective Antibiotics regimen with placebo is beyond my
understanding.

Competing interests:
None declared

Competing interests: No competing interests

09 December 2003
Dhirrendra P Singh
Clinical Fellow in Paediatrics
N18 1QX
North Middlesex University Hospital, London