Intended for healthcare professionals

Rapid response to:


Rofecoxib caused excess heart disease

BMJ 2005; 330 doi: (Published 27 January 2005) Cite this as: BMJ 2005;330:212

Rapid Response:

Is naproxen safe?

We learn that naproxen use has a 14% increased risk of coronary heart
disease compared with other non-steroidal anti-inflammatory drugs.

The Lancet article's authors merely talk about naproxen's "lack of
protective effect". Aren't they being a little timid? Is 14% a low enough
figure to ignore, as everyone seems to be doing? At what point do we/our
patients start to panic and stockholders hastily review their portfolios:-
18%, 20%?

Competing interests:
None declared

Competing interests: No competing interests

31 January 2005
Peter J Flegg
Blackpool, FY3 8NR