Intended for healthcare professionals

Rapid response to:


Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies

BMJ 2005; 330 doi: (Published 10 March 2005) Cite this as: BMJ 2005;330:565

Rapid Response:

EBM can confound

Paternal factors may well also be relevant as risk factors for pre- eclampsia [1], a relationship I first heard of in Ibadan in 1978. No doubt there are no good controlled studies to support this assertion so correctly Duckitt and Harrington did not include this factor in their list. (Family history is included but only maternal family history)

And yet their list is likely to be oft quoted as a definitive list, but in fact it is only a list of those factors that have level I evidence to support them. I am a great fan of Evidence Based Medicine, but do feel that articles like this should at least mention other known factors - this would ensure a better perspective for the majority of readers who can not read every article in great depth.

Dr D H Jobson General Practitioner and sometime Obstetrician in the Gambia. [1] BMJ 1998;316:1343-1347 ( 2 May )

Competing interests: None declared

Competing interests: No competing interests

12 March 2005
David Jobson
Retired GP & Obstetrician