Intended for healthcare professionals

Rapid response to:

Papers

A strategy to reduce cardiovascular disease by more than 80%

BMJ 2003; 326 doi: https://doi.org/10.1136/bmj.326.7404.1419 (Published 26 June 2003) Cite this as: BMJ 2003;326:1419

Rapid Response:

drug interactions

Six drugs produce fifteen potential 2-drug combinations and twenty
potential three-drug combinations. If the recipient of the polypill adds
an over-the-counter pain reliever for his/her arthritis or headaches, the
potential two-drug combinations rise to 21 and three-drug combinations to
35. Imagine the possibilties if the drug recipient takes a few herbal
remedies plus a multi-vitamin supplement, and drinks alcohol regularly,
not to mention potential food-drug interactions!

Given that medication-related problems consitute a major cause of
hospitalization among the elderly, why would we choose to compound the
problem by administering drugs to those who clearly do not need them?

Competing interests:  
None declared

Competing interests: No competing interests

18 September 2003
Teresa Tarnowski Goodell, RN
clinical nurse specialist
research consultant - Portland, Oregon, USA