Risk of lowering risk factors
The logarithm of incidence of ischemic heart disease may be
proportional to several risk factors such as diastolic blood pressure,
serum cholesterol, and body mass index. The authors draw the conclusion
that more interventions are justified than are currently performed aiming
to reduce even moderately or hardly elevated risk factors.
How would a non
-zero risk of the intervention itself affect that conclusion? Wouldn’t
there be a level of risk factor at which the risk of the intervention
outweighs the benefit of further lowering the risk factor?
Thus the risk
of intervention would set a threshold for lowering risk factors to be
useful for the patient.
Competing interests: No competing interests