Intended for healthcare professionals

Rapid response to:

Primary Care

Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database

BMJ 2002; 325 doi: (Published 24 August 2002) Cite this as: BMJ 2002;325:419

Rapid Response:

Re: GI and Autism

......and the silence is deafening. Though a wealth of material and
research exists to support the prevalance of gut dysbiosis in ASD
individuals, still there is relatively little official support for simple
non-invasive and often successful dietary intervention.

Though the Question of causation remains shrouded in relative mystery
with competing agendas governing what is deemed worthy of further
research, we have what seems to be a partial Answer.

A growing body of parents would quite happily document their childs
progress in health and wellbeing having instituted this diet, witnessed by
those involved in the childs education. Too often (as has been mentioned
in other contributors varied postings on this thread) the parents I am in
contact with note that no history of GI problems exist on their childs
medical record, once a diagnosis of ASD has been given, all else appears
to fall by the wayside.

The Allergy Research Foundation have recently issued the first
announcement of a meeting to be held in London October 29th 2003.

Allergy and Nutrition in the Autistic Spectrum Disorder

The proposed meeting is described as:

"Over time it has become clear that there is a group of children
whose symptoms and behaviour fall into a matrix, showing some of the
symptoms of the Autistic spectrum and some symptoms of the Attention
Deficit Spectrum.

A link between Attention Deficit in some children and dietary factors
has been recognised for many years.More recently workers have suggested
that some children within the Autistic spectrum can also respond to
changes in their diet.

At this meeting evidence will be presented to show that a common
factor in both these groups is a disorder within the bowel, possibly
linked to "Gut Dysbiosis" The meeting will explore whether there is a sub-
group of children with Attention Deficit,Autistic Spectrum or the matrix
of both conditions who have slightly different expressions of the same
underlying disturbance of gut function.

There may be an opportunity to examine whether the variable
expression relates to genetic predisposition, age of onset of symptoms or
other triggers affecting the response to the bowel disorder"

Several medical and academic speakers will present their current
research and case studies; as the programme is as yet provisional I will
not list them here. I do hope that some of you who may work with ASD
children create the opportunity to be present and participate in this


The Allergy Research Foundation can be contacted for further details
as follows:
Tel/Fax: +44(0)1296-655818

Competing interests:  
None declared

Competing interests: No competing interests

06 July 2003
M C Feliciello