Intended for healthcare professionals

Rapid response to:


Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials

BMJ 2003; 326 doi: (Published 26 June 2003) Cite this as: BMJ 2003;326:1427

Rapid Response:

Err... where's the clinical trial?

One of the great advantages of merely aggregating the
research of others into grand strategies is that it
removes one from the tedium of enquiring after
individual patients' well-being.

Clinicians who do this on a regular basis will I am sure
agree that the drug without any adverse effects in
anybody has yet to be found; and yes, one should feel a
certain scruple about encouraging healthy,
asymptomatic people to take any medication which
may make them feel ill, never mind six.

Wald et al have an interesting hypothesis: now let us
have data from real life randomised controlled trials of
their proposed treatment. Perhaps, if it saves lives, and
does not poison people too badly, your editorial hype
will be justified.

Competing interests:  
None declared

Competing interests: No competing interests

27 June 2003
Douglas J Carnall
London, E8 1AJ