Was the risk of ischemic heart analyzed for anti-depressant drugs?
It is a well known fact that tricyclic anti depressants(TCA)
may induce increased catecholamine activity which may be serious in an
Also A - V nodal bradycardia has been noted in depressed patients, so
that TCAs may depress the alpha adrenergic receptors and induce
orthostatic hypotension with reflex tacycardia
The point being that adverse effects of TCAs may be the real problem
in provoking ischemic heart disease symptoms rather than depresion in or
Munir E Nassar, M.D.
Competing interests: No competing interests