Intended for healthcare professionals

Rapid response to:


Birth characteristics of women who develop gestational diabetes: population based study

BMJ 2000; 321 doi: (Published 02 September 2000) Cite this as: BMJ 2000;321:546

Rapid Response:

Smoking may cause familial gestational diabetes and low birtweight

To the Editor:

At least within the tobacco industry, smoking has long been a well
known cause of hyperglycemia and low birth weight.1 Smoking runs in
families.2 Smoking is suspected to cause gestational3 4 as well as Type 2
diabetes.5 6 Thus smoking may explain some or all of the findings in this
study and should be a) excluded as a cause of the study findings before
accepting the authors conclusions and b) a major focus in care for
pregnancy, diabetes, and families.

I have no funding or conflicts of interest in relation to this study
or this letter.

1. Nicotine Review: British American Tobacco (BAT), ~1983.,
accessed 8/29/00

2. Charlton A. Children and smoking: the family circle. Br Med Bull

3. Zaren B, Lindmark G, Wibell L, Folling I. The effect of smoking on
glucose homeostasis and fetal growth in pregnant women [In Process
Citation]. Ups J Med Sci 2000;105(1):41-56.

4. Solomon CG, Willett WC, Carey VJ, Rich-Edwards J, Hunter DJ,
Colditz GA, et al. A prospective study of pregravid determinants of
gestational diabetes mellitus. Jama 1997;278(13):1078-83.

5. Nakanishi N, Nakamura K, Matsuo Y, Suzuki K, Tatara K. Cigarette
smoking and risk for impaired fasting glucose and type 2 diabetes in
middle-aged Japanese men. Ann Intern Med 2000;133(3):183-91.

6. Rimm EB, Manson JE, Stampfer MJ, Colditz GA, Willett WC, Rosner B,
et al. Cigarette smoking and the risk of diabetes in women. Am J Public
Health 1993;83(2):211-4.

Competing interests: No competing interests

01 September 2000
Bruce N Leistikow
Adjunct Associate Professor
University of California, Davis