Length of penicillin treatment of streptococcal infections
The author recommends a 7 days treatment for streptococcal
infections as opposed to 3 days. For several decades we were educated to
continue penicillin for such cases for a period of 10 days , and no less !
The rationale was that eradication of streptococci is necessary to prevent
rheumatic fever and was achievable only after 10 days of treatment . This
was apparently based on bacteriological, epidemiological and clinical
observations. The cost of oral penicillin is almost negligible and I think
we need more assurance to be persuaded to cut treatment to only 7 days.
Is there any study that will prove that 7 days are as effective as 10 for
preventing rheumatic fever ?
Ref: Christie A.B. Infectious Diseases: Epidemiology and Clinical
Practice, E.& S. Livingstone editors ,1969 p.983.
Competing interests: No competing interests