Antioxidants to quench free radicals in solar retinal burn
Since much evidence exists for the involvement of free radicals in
the mechanism of burn injuries* it is reasonable to assume that immediate
oral or IV ascorbate* and a suitable form of d-alpha-tocopherol* IV,
would be effective in the prevention of lifelong central scotoma at least
in borderline cases of solar burn.
I am certain that Prof Denham Harman M.D., Ph.D. Emeritus, Nebraska
Univ. (Father of the Free Radical Teory of Ageing and Disease 1954) with
whom I am in regular communication, would endorse this view.
Free Radic Biol Med 1998 Dec;25(9):1006-12
Modulation of UV-light-induced skin inflammation by D-alpha-
tocopherol and L-ascorbic acid: a clinical study using solar simulated
radiation.
Fuchs J, Kern H
Department of Dermatology, Medical School, J.W. Goethe University,
Frankfurt, Germany.
Rapid Response:
Antioxidants to quench free radicals in solar retinal burn
Since much evidence exists for the involvement of free radicals in
the mechanism of burn injuries* it is reasonable to assume that immediate
oral or IV ascorbate* and a suitable form of d-alpha-tocopherol* IV,
would be effective in the prevention of lifelong central scotoma at least
in borderline cases of solar burn.
I am certain that Prof Denham Harman M.D., Ph.D. Emeritus, Nebraska
Univ. (Father of the Free Radical Teory of Ageing and Disease 1954) with
whom I am in regular communication, would endorse this view.
Free Radic Biol Med 1998 Dec;25(9):1006-12
Modulation of UV-light-induced skin inflammation by D-alpha-
tocopherol and L-ascorbic acid: a clinical study using solar simulated
radiation.
Fuchs J, Kern H
Department of Dermatology, Medical School, J.W. Goethe University,
Frankfurt, Germany.
Competing interests: No competing interests