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Papers

Inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: retrospective cohort study

BMJ 2001; 323 doi: https://doi.org/10.1136/bmj.323.7314.655 (Published 22 September 2001) Cite this as: BMJ 2001;323:655

Rapid Response:

Antidepressants and GI bleeding

Sir,

I read the BMJ for information, stimulation and entertainment. In the
first category I seek papers that may have implications for my everyday
practice and that on antidepressants and gastrointestinal bleeding
appeared to be one such.

I found the information interesting and probably relevant but have
been unable to review or modify my practice as I do not know the relative
strength of serotonin uptake inhaibition of the antidepressants I
prescribe. In fact I am not aware that there is a difference in potency at
the commonly used doses.

I accept that perhaps that this is something I should know, though I
could find no reference for scales of potency of serotonin uptake cited.

However in the meantime the usefulness of this paper to practising
doctors could be greatly enhanced by a table listing the differing
strength of serotonin uptake of the commonly used antidepressants.

Yours

Charles Campion-Smith MB ChB DCH FRCGP

Competing interests: No competing interests

17 October 2001
Charles Campion-Smith
GP / Primary Care Educator
15 Cornwall Road, Dorchester, Dorset