Obesity and the risk of toxaemia of pregnancy

Ann Hum Biol. 1996 Sep-Oct;23(5):353-62. doi: 10.1080/03014469600004602.

Abstract

The purpose of the present study was to examine the relationship between severe pre-eclampsia/eclampsia (toxaemia) and obesity. We collected sociodemographic, anthropometric, medical and pregnancy outcome data from the hospital records of 248 Israeli women diagnosed with either pregnancy-induced or chronic hypertension, and compared these data to a control group of 236 women. Univariate analysis showed that while there exists a statistically significant positive association between obesity and hypertension (both pregnancy-induced and chronic) obesity presents no added risk to the development of toxaemia. Furthermore, we found a significant decrease in the rate of obesity among primigravid versus multigravid mothers with toxaemia superimposed on pregnancy-induced hypertension. On the other hand, primigravid mothers with PIH were at an increased risk of developing toxaemia as compared to multigravid women. These results suggest that obesity is not a significant factor in the development of toxaemia.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Case-Control Studies
  • Eclampsia / etiology
  • Female
  • Humans
  • Hypertension / etiology
  • Israel
  • Obesity / complications*
  • Pre-Eclampsia / etiology*
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / etiology
  • Pregnancy Outcome
  • Risk Factors