Objective: To determine the effect of moderate alcohol intake on probability of conception.
Design: Prospective cohort study.
Setting: Normal healthy women enrolled in an artificial donor insemination program.
Patients: Women starting artificial donor insemination for the very first time were selected.
Interventions: Alcohol exposure was measured through a self-administered questionnaire at intake of study.
Main outcome measure: A first positive pregnancy test as indicative for conception.
Results: Women with moderate alcohol intake had a slightly higher, though not significant, probability of conception compared with nondrinkers (Hazard Ratio 1.20; 95% confidence interval 0.90 to 1.60).
Conclusion: Moderate alcohol intake has no negative impact on female fecundity.