Abstract
Three cases of meningitis and two of septicaemia were caused by pneumococci resistant to the penicillins/cephalosporins and chloramphenicol. No beta-lactamase was demonstrated in any of the organisms. All three patients with meningitis died, but the patients with septicaemia recovered after being given appropriate antibiotic therapy.
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use
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Child, Preschool
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Drug Resistance, Microbial
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Humans
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Infant
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Meningitis, Pneumococcal / drug therapy*
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Meningitis, Pneumococcal / microbiology
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Microbial Sensitivity Tests
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Sepsis / drug therapy*
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Sepsis / microbiology
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South Africa
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Streptococcal Infections / drug therapy*
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Streptococcal Infections / microbiology
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Streptococcus pneumoniae / drug effects*