Abstract
The effects of addition of 1 ml of lignocaine (10 mg) or isotonic saline to 19 ml of the emulsified preparation of propofol (Diprivan) were studied in a randomised, double-blind trial in 80 patients. The incidence and severity of pain on injection of propofol were significantly reduced by the addition of lignocaine (P less than 0.01).
Publication types
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Clinical Trial
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Anesthesia, Intravenous / adverse effects*
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Anesthetics / administration & dosage*
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Double-Blind Method
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Female
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Humans
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Injections, Intravenous / adverse effects
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Lidocaine / administration & dosage*
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Middle Aged
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Pain / prevention & control*
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Phenols / administration & dosage*
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Propofol
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Random Allocation
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Sodium Chloride / administration & dosage
Substances
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Anesthetics
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Phenols
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Sodium Chloride
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Lidocaine
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Propofol