Recovery after critical illness: putting the puzzle together-a consensus of 29

Elie Azoulay; Jean-Louis Vincent; Derek C Angus; Yaseen M Arabi; Laurent Brochard; Stephen J Brett; Giuseppe Citerio; Deborah J Cook; Jared Randall Curtis; Claudia C Dos Santos; E Wesley Ely; Jesse Hall; Scott D Halpern; Nicholas Hart; Ramona O Hopkins; Theodore J Iwashyna; Samir Jaber; Nicola Latronico; Sangeeta Mehta; Dale M Needham; Judith Nelson; Kathleen Puntillo; Michael Quintel; Kathy Rowan; Gordon Rubenfeld; Greet Van den Berghe; Johannes Van der Hoeven; Hannah Wunsch; Margaret Herridge

doi:10.1186/s13054-017-1887-7

Recovery after critical illness: putting the puzzle together-a consensus of 29

Crit Care. 2017 Dec 5;21(1):296. doi: 10.1186/s13054-017-1887-7.

Authors

Elie Azoulay¹, Jean-Louis Vincent², Derek C Angus³, Yaseen M Arabi⁴, Laurent Brochard⁵, Stephen J Brett⁶, Giuseppe Citerio⁷, Deborah J Cook⁸, Jared Randall Curtis⁹, Claudia C Dos Santos¹⁰, E Wesley Ely¹¹, Jesse Hall¹², Scott D Halpern¹³, Nicholas Hart¹⁴, Ramona O Hopkins^{15

16}, Theodore J Iwashyna¹⁷, Samir Jaber¹⁸, Nicola Latronico¹⁹, Sangeeta Mehta²⁰, Dale M Needham²¹, Judith Nelson²², Kathleen Puntillo²³, Michael Quintel²⁴, Kathy Rowan²⁵, Gordon Rubenfeld²⁶, Greet Van den Berghe²⁷, Johannes Van der Hoeven²⁶, Hannah Wunsch²⁸, Margaret Herridge²⁹

Affiliations

¹ Medical Intensive Care Unit, Hôpital Saint-Louis, ECSTRA team, Biostatistics and clinical epidemiology, UMR 1153 (Center of Epidemiology and Biostatistics Sorbonne Paris Cité, CRESS), INSERM, Paris Diderot Sorbonne University, Paris, France. elie.azoulay@sls.aphp.fr.
² Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium.
³ The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
⁴ King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
⁵ St. Michael's Hospital, Toronto, ON, Canada.
⁶ Department of Surgery and Cancer Imperial College, London, UK.
⁷ Università Milano Bicocca, Milano, Italy.
⁸ McMaster University Medical Center, Hamilton, ON, Canada.
⁹ Cambia Palliative Care Center of Excellence, Seattle, WA, USA.
¹⁰ Toronto General Research Institute, University of Toronto, Toronto, ON, Canada.
¹¹ Vanderbilt University School of Medicine, and TN Valley Veteran's Affairs Geriatric Research Education Clinical Center (GRECC), Nashville, TN, USA.
¹² The University of Chicago, Chicago, IL, USA.
¹³ Perelman School of Medicine, Philadelphia, PA, USA.
¹⁴ St Thomas Hospital, London, UK.
¹⁵ Intermountain Medical Center, Murray, UT, USA.
¹⁶ Psychology Department and Neuroscience Center, Brigham Young University, Provo, UT, USA.
¹⁷ University of Michigan Health System, and Ann Arbor Veterans Affairs Healthcare System, Ann Arbor, MI, USA.
¹⁸ Saint-Eloi Hospital, Montpellier, France.
¹⁹ University of Brescia at Spedali Civili, Brescia, Italy.
²⁰ Mount Sinai Hospital, Toronto, ON, Canada.
²¹ Johns Hopkins University School of Medicine, Baltimore, MD, USA.
²² Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College New York, New York, NY, USA.
²³ University of California, San Francisco, CA, USA.
²⁴ University Hospital Göttingen, Göttingen, Germany.
²⁵ Intensive Care National Audit & Research Centre, London, UK.
²⁶ Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
²⁷ University Hospital Leuven, Leuven, Belgium.
²⁸ Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
²⁹ Toronto General Research Institute, University of Toronto, UHN - University Health Network, Toronto, ON, Canada.

Abstract

In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new insights into ICU acquired weakness, to emphasize the importance of value-based healthcare, and to delineate the elements of family-centered care. This consensus of 29 also provides a perspective and a research agenda about post-ICU recovery.

Keywords: Cognitive dysfunction; Delirium; Depression; Intensive care; Mechanical ventilation; Muscular disorder; Sedation; Traumatic stress; Weakness.

Publication types

Review

MeSH terms

Consensus
Critical Illness / psychology*
Critical Illness / rehabilitation*
Deep Sedation / adverse effects
Deep Sedation / methods
Delirium / epidemiology
Delirium / etiology*
Humans
Intensive Care Units / organization & administration
Length of Stay
Long Term Adverse Effects / etiology*
Pain Management / adverse effects
Pain Management / methods
Respiration, Artificial / adverse effects
Respiration, Artificial / methods
Time Factors