Sacrospinous hysteropexy: review and meta-analysis of outcomes

Int Urogynecol J. 2017 Sep;28(9):1285-1294. doi: 10.1007/s00192-017-3291-x. Epub 2017 Mar 3.

Abstract

Introduction: Sacrospinous hysteropexy is a uterine-preserving procedure for treatment of apical prolapse. We present a literature review evaluating the sacrospinous hysteropexy procedure and its current place in the surgical management of pelvic organ prolapse. Additionally, to assess the efficacy of the procedure, we performed a meta-analysis of studies comparing sacrospinous hysteropexy to vaginal hysterectomy and repair in terms of anatomical outcomes, complications, and repeat surgery.

Methods: Major literature databases including MEDLINE (1946 to 2 April 2016), Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 3), and Embase (1947 to 2 April 2016) were searched for relevant studies. We used Cochrane Collaboration's Review Manager software to perform meta-analysis of randomized controlled studies and observational studies.

Results: Vaginal sacrospinous hysteropexy was first performed in 1989 and is similar in technique to sacrospinous colpopexy. Two randomized controlled trials and four cohort studies (n = 651) were included in the meta-analysis. Apical failure rates after sacrospinous hysteropexy versus vaginal hysterectomy were not significantly different, although the trend favored vaginal hysterectomy [odds ratio (OR) 2.08; 95% confidence interval (CI) 0.76-5.68]. Rates of repeat surgery for prolapse were not significantly different between the two groups (OR 0.99; 95% CI 0.41-2.37). The most significant disadvantage of uterine-preservation prolapse surgery when compared with hysterectomy is the lack of prevention and diagnosis of uterine malignancy.

Conclusion: Sacrospinous hysteropexy is a safe and effective procedure for pelvic organ prolapse and has comparable outcomes to vaginal hysterectomy with repair.

Keywords: Apical prolapse; Sacrospinous hysteropexy; Uterine preservation; Vaginal hysterectomy.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Female
  • Humans
  • Hysterectomy, Vaginal / methods
  • Hysteroscopy / methods*
  • Organ Sparing Treatments / methods*
  • Pelvic Organ Prolapse / surgery*
  • Sacrum / surgery
  • Spine / surgery
  • Treatment Outcome
  • Uterus / surgery
  • Vagina / surgery