Detection of bloodstream infections and prediction of bronchopulmonary dysplasia in preterm neonates with an electronic nose

Tobias Rogosch; Nina Herrmann; Rolf F Maier; Eugen Domann; Akira Hattesohl; Andreas Rembert Koczulla; Michael Zemlin

doi:10.1016/j.jpeds.2014.04.049

Detection of bloodstream infections and prediction of bronchopulmonary dysplasia in preterm neonates with an electronic nose

J Pediatr. 2014 Sep;165(3):622-4. doi: 10.1016/j.jpeds.2014.04.049. Epub 2014 Jun 11.

Authors

Tobias Rogosch¹, Nina Herrmann¹, Rolf F Maier¹, Eugen Domann², Akira Hattesohl³, Andreas Rembert Koczulla³, Michael Zemlin⁴

Affiliations

¹ Department of Pediatrics, Philipps-University Marburg, Marburg, Germany.
² Division for Pulmonary Diseases, Department of Internal Medicine, Philipps-University Marburg, Marburg, Germany.
³ Institute of Medical Microbiology, Justus-Liebig-University, Giessen, Germany.
⁴ Department of Pediatrics, Philipps-University Marburg, Marburg, Germany. Electronic address: zemlin@med.uni-marburg.de.

PMID: 24929333
DOI: 10.1016/j.jpeds.2014.04.049

Abstract

We show that smellprints of volatile organic components measured with an electronic nose (Cyranose 320; Smiths Detection Group Ltd, Watford, United Kingdom) differ between tracheal aspirates from preterm neonates with or without laboratory-confirmed bloodstream infections and with or without subsequent development of bronchopulmonary dysplasia. Tracheal aspirate smellprints could be useful noninvasive diagnostic markers for preterm neonates.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteremia / complications*
Bacteremia / diagnosis*
Body Fluids
Bronchopulmonary Dysplasia / complications*
Bronchopulmonary Dysplasia / diagnosis*
Electronic Nose*
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / diagnosis*
Predictive Value of Tests
Trachea