β-boswellic acid (BA), one major constituent of the resin of Boswellia serrata and other triterpenic acids of plant origin (crataegolic-, ursolic-, oleanolic- and glycyrrhetic acid) were found to possess anti-complementary activity in the classical and in the alternative complement pathway. Significant reduction of immunohemolysis in vitro was observed at BA concentrations between 0.005-0.1 mM with an IC(50) value of about 10 μmol/l.
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