[Study of the real situation of improvement by Zopiclone in treatment of insomnia among persons working during night shifts]

Rev Neurol (Paris). 2002 Nov;158(11):1102-6.
[Article in French]

Abstract

We investigated the effect of adapted management of sleep on the duration and quality of sleep in shift workers working the night shift. Twenty-nine shift workers suffering from insomnia were included and treated with zopiclone (7.5mg/day) or placebo according to a random double-blind protocol. Patients completed a sleep diary and a wrist actigraph was used to evaluate episodes of rest/activity. A self-administered subjective sleep questionnaire was filled out just after awakening. Zopicone was found to increase the duration of sleep significantly (p<0.05) over the baseline duration after the first and second night on duty. Subjective estimation of sleep was better in patients taking zopiclone who exhibited a smaller number of shorter awakening episodes.

In conclusion: zopiclone improves the quality and duration of sleep in shift workers suffering from insomnia.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Azabicyclo Compounds
  • Humans
  • Hypnotics and Sedatives / therapeutic use*
  • Male
  • Middle Aged
  • Occupational Diseases / drug therapy*
  • Piperazines / therapeutic use*
  • Sleep Disorders, Circadian Rhythm / drug therapy*
  • Wakefulness

Substances

  • Azabicyclo Compounds
  • Hypnotics and Sedatives
  • Piperazines
  • zopiclone