ARTISTIC: a randomised trial of human papillomavirus (HPV) testing in primary cervical screening

Kitchener, HC; Almonte, M; Gilham, C; Dowie, R; Stoykova, B; Sargent, A; Roberts, C; Desai, M; Peto, J

doi:10.3310/hta13510

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This study found that it would not be either effective or cost-effective to screen with cytology and human papillomavirus (HPV) combined when compared with liquid-based cytology alone. HPV testing, either as triage or as initial test triaged by cytology, would be cheaper than cytology without HPV testing

HC Kitchener, M Almonte, C Gilham, R Dowie, B Stoykova, A Sargent, C Roberts, M Desai & J Peto.

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HC Kitchener ^1,^*, M Almonte ², C Gilham ², R Dowie ³, B Stoykova ³, A Sargent ¹, C Roberts ⁴, M Desai ⁵, J Peto ^2,⁶

¹ School of Cancer and Imaging Sciences, University of Manchester, St Mary’s Hospital, Manchester, UK
² Non-Communicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, London, UK
³ Health Economics Research Group, Brunel University, Uxbridge, UK
⁴ Biostatistics Group, University of Manchester, Manchester, UK
⁵ Department of Cytology, Central Manchester and Manchester Children’s University Hospitals NHS Trust, Manchester, UK
⁶ Institute of Cancer Research, Sutton, UK
^* Corresponding author Email: henry.kitchener@manchester.ac.uk

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