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A 12-Hour Urine Collection Accurately Assesses Proteinuria in the Hospitalized Hypertensive Gravida

Journal of Perinatology volume 19, pages 556–558 (1999)Cite this article

Abstract

OBJECTIVE:

To determine whether a urine collection of <24 hours duration accurately assesses the level of proteinuria in inpatients being evaluated for preeclampsia.

STUDY DESIGN:

Patients admitted to the University of Mississippi between January and June of 1998 for evaluation of preeclampsia underwent two consecutive 12-hour urine collections. Each collection was analyzed for total protein, total calcium, total volume, and urine creatinine. A concurrent serum creatinine value was obtained. The protein:creatinine ratio, calcium:creatinine ratio, and creatinine clearance were calculated. Pearson’s correlation, sensitivity, specificity, and positive and negative predictive values were assessed.

RESULTS:

A total of 25 patients (86%) were preeclamptic. Total protein, the protein:creatinine ratio, and serum creatinine were significantly correlated between the first and second urine collection. The sensitivity and specificity of the 12-hour urine collection was 96% and 100%, respectively.

CONCLUSION: A 12-hour urine collection accurately depicts the amount of proteinuria in hospitalized gravidas being evaluated for preeclampsia.

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Authors and Affiliations

  1. Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, Mississippi

    Brian K Rinehart MD, Dom A Terrone MD, J Elaine Larmon MD, Kenneth G Perry Jr. MD, Rick W Martin MD & James N Martin Jr. MD

Authors
  1. Brian K Rinehart MD
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  2. Dom A Terrone MD
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  3. J Elaine Larmon MD
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  4. Kenneth G Perry Jr. MD
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  5. Rick W Martin MD
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  6. James N Martin Jr. MD
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Additional information

This work was supported in part by the Vicksburg Hospital MedicalFoundation, Vicksburg, Mississippi.

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Rinehart, B., Terrone, D., Larmon, J. et al. A 12-Hour Urine Collection Accurately Assesses Proteinuria in the Hospitalized Hypertensive Gravida. J Perinatol 19, 556–558 (1999). https://doi.org/10.1038/sj.jp.7200271

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  • DOI: https://doi.org/10.1038/sj.jp.7200271

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