Elsevier

Microbes and Infection

Volume 8, Issue 7, June 2006, Pages 1891-1897
Microbes and Infection

Forum on antimicrobial resistance
The clonal spread of multidrug-resistant non-typhi Salmonella serotypes

https://doi.org/10.1016/j.micinf.2005.12.020Get rights and content
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Abstract

Non-typhoid Salmonella are one of the most important organisms causing food-borne diseases worldwide. There have been significant increases in developed countries in recent years in the occurrence of resistance, in particular multidrug resistance phenotypes, in non-typhoid Salmonella spp. Such increases have been observed in many countries, not only within the European community but also the Americas and Southeast Asia. Of particular concern is the increasing detection of Salmonella isolates displaying resistance to key antimicrobials, notably fluoroquinolones and third-generation cephalosporins. An important factor associated with this increase in multidrug resistance among particular Salmonella spp. is the national and international spread of certain clonal genotypes, the most recent being the global epidemic spread of multidrug-resistant S. Typhimurium DT104, since the early 1990s. In this review, we describe examples where particular antimicrobial-resistant Salmonella serotypes emerged, persisted for periods of time, and then quickly decreased in prevalence.

Keywords

Antibiotic
Resistance
Salmonella
Epidemiology

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