Research LettersMale circumcision and risk of HIV-1 and other sexually transmitted infections in India
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Susceptibility to human immunodeficiency virus-1 infection of human foreskin and cervical tissue grown in explant culture
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Effect of circumcision on incidence of human immunodeficiency virus type 1 and other sexually transmitted diseases: a prospective cohort study of trucking company employees in Kenya
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Cited by (137)
HIV/AIDS Prevention
2023, Manson's Tropical Diseases, Fourth EditionAsian guidelines for genital herpes
2021, Journal of Infection and ChemotherapyMedical male circumcision and HIV prevention among men in Kwazulu-Natal, South Africa: A propensity score analysis
2021, Scientific AfricanCitation Excerpt :Other studies [8,9], also produced similar findings. Many observational studies, including systematic reviews and meta-analyses, have found a protective effect of male circumcision against HIV infection [10–14]. By their nature of being observational, all these studies were limited in terms of their inability to determine a causal effect of male circumcision on protection against HIV infection.
Pros and cons of circumcision: an evidence-based overview
2016, Clinical Microbiology and InfectionCitation Excerpt :Based on observational studies conducted in the USA, it is likely that circumcision both prevents HPV and increases the likelihood for clearing existing HPV infections [36,37]. Data on HSV are conflicting as a cohort study conducted in Australia showed a protective effect of circumcision, whereas trials in America and India failed to demonstrate such an effect [38–40]. Studies conducted in the USA, India, and Austria demonstrated conflicting results with regard to the effect of circumcision on the incidence of HSV and syphilis [38–41].
Human Male Genital Tract Immunity
2015, Mucosal Immunology: Fourth EditionA review of the current state of the male circumcision literature
2014, Journal of Sexual MedicineCitation Excerpt :With technological advances allowing the surgical risks of circumcision to be minimized, there has been a shift in circumcision research towards observational/cohort and randomized controlled trials (RCTs) that have demonstrated a reduction in the risk of STI acquisition and transmission in circumcised as compared with intact men. Evidence exists for lower rates of transmission of HIV [2–4], ulcerative STIs (syphilis, genital herpes simplex, chancroid, and lymphogranuloma venereum infections [10,11]; but also see [12]), and HPV [13–18] (but also see [19]) in circumcised as compared with intact men. Other health benefits of circumcision include lower rates of urinary tract infections in male infants [20–23], lower rates of penile cancer [24,25] (but also see [26,27]), and lower rates of inflammatory dermatoses (e.g., balanoposthitis [28]).