Table 1

Baseline characteristics of included cohorts

Study nameEthnicityCountryNo of participantsFollow-up (years)Men (%)Age (years)SBP (mm Hg)Hypertension (%)Antihypertensive drugs (%)rs4988235 frequency (%)
CCCTTT
CGPSWhiteDenmark74 21904557140202063658
WGHSWhiteUSA19 74340541261313113851
GESUSWhiteDenmark14 81504657142102363658
NHSWhiteUSA11 28726053NA9NA144145
ARIC (white)WhiteUSA82336475411829199*39*52*
ARIC (African-American)AfricanUSA188963653127554174*25*2*
HPFSWhiteUSA69142410055NA22NA183943
INTER99WhiteDenmark65145494613031763657
D.E.S.I.R.WhiteFrance337895047131359224930
Rotterdam StudyWhiteNetherlands321574166136542793952
MDCSWhiteSweden3199174056139531463361
GLACIERWhiteSweden276310374512419473658
MESAMixedUSA24241047611323528204930
FamHSWhiteUSA2167845511274436124246
CHSWhiteUSA196493871133493544353
YFSWhiteFinland13700433812097154738
DCH Study‡WhiteDenmark129704556135471353263
DIOGENES‡ (controls)WhiteDenmark10020515413538763658
DIOGENES‡ (weight gainers)WhiteDenmark81304953135421053560
PREDIMED-VALENCIAWhiteSpain940236671478463384616
BPRHSPuerto RicanUSA84502857136785661345
GOLDNWhiteUSA818050491182621104050
RaineMixed§Australia7282482011740153946
InCHIANTIWhiteItaly64704564142644923068

See web appendix for full titles of studies.

SBP=systolic blood pressure.

*rs1446585 used as a proxy.

†rs309137 used as a proxy.

‡Subsamples from Danish Diet, Cancer and Health cohort.

§Dominantly white, white-admixed (participants with one or both white parents).