Table 3

 Radiographic outcomes (n=175)

Dose reduction (n=116)Usual care (n=59)Difference (95% CI)
Progression total SvdH score*0.75 (1.5)0.15 (1.1)0.60 (0.17 to 1.0)
Progression erosion score*0.29 (0.8)0.12 (0.7)0.17 (−0.07 to 0.41)
Progression joint space narrowing*0.46 (1.2)0.03 (0.9)0.43 (0.08 to 0.78)
Progression >minimal clinical important change (8 units)†000% (−8% to 4%)
Progression >smallest detectable change (4.1 units)†5 (4%)04% (−4% to 10%)
Progression >0.5 units†37 (32%)9 (15%)17% (2% to 29%)

Progression=in units per 18 months.

*Mean (standard deviation).

†Number (%) of patients.