Table 1

 Demonstration pragmatic trial pilots of the NIH Health Care Systems Research Collaboratory funded in 2012

Project titleResearch questionPrincipal investigatorPartner organizations
Strategies and Opportunities to Stop Colon Cancer in Priority Populations (STOP CRC)Does an evidence based, culturally tailored approach increase colorectal cancer screening in minority and low income populations?Gloria Coronado, Kaiser Permanente NorthwestKaiser Foundation Hospitals; Oregon Community Health Information Network (OCHIN); Federally Qualified Health Center clinics
Collaborative Care for Chronic Pain in Primary Care (PPACT)Does a team based program in primary care help patients manage chronic pain?Lynn DeBar, Kaiser Permanente NorthwestKaiser Permanente Georgia; Kaiser Permanente Northwest; Kaiser Permanente Hawaii
Time to Reduce Mortality in End-Stage Renal Disease (TiME)Does systematically implementing a hemodialysis session duration of ≥4.25 hours improve survival, reduce hospitalizations, and improve quality of life for patients with kidney failure?Laura Dember, University of PennsylvaniaDialysis provider organizations Fresenius Medical Care-North America and DaVita
Bathing to Eliminate Infection (ABATE Infection)Does routine bathing with antiseptic soap (compared with targeted use of a nasal antibiotic ointment) reduce infections and hospital readmissions in general medical, surgical, and oncology inpatient units?Susan Huang, University of California Irvine School of MedicineHospital Corporation of America; Harvard Pilgrim Health Care; John Stroger Hospital of Cook County; Rush University
A Pragmatic Trial of Lumbar Image Reporting with Epidemiology (LIRE)Can interpretation of diagnostic tests for lower back pain be improved by adding information to imaging reports on the prevalence of findings in patients without back pain?Jeffrey Jarvik, University of WashingtonKaiser Permanente Northern California; Group Health Cooperative; Mayo Clinic; Henry Ford Health System
Pragmatic Trial of Population-Based Programs to Prevent Suicide AttemptHow well do two different intervention programs work to reduce suicide risk?Gregory Simon, Group Health Research InstituteGroup Health Cooperative; HealthPartners; Kaiser Permanente Colorado
Nighttime Dosing of Anti-Hypertensive Medications: A Pragmatic Clinical Trial (BPMedTime)Does nighttime dosing of blood pressure medication reduce risk for cardiovascular events?Gary Rosenthal, University of IowaUniversity of Iowa, Duke University