Table 1.

Sensitivity, specificity, and likelihood ratios of screening questions for depression in primary care, help question, combination of screening and help questions, and general practitioner diagnosis

Variable% sensitivity (95% CI)True positive responses% specificity (95% CI)True negative responsesPositive likelihood ratio (95% CI)Negative likelihood ratio (95% CI)
Help question alone75 (60 to 85)3594 (93 to 96)83813.0 (9.5 to 17.8)0.27 (0.17 to 0.44)
Two screening questions alone96 (86 to 99)4578 (76 to 81)6974.4 (3.9 to 5.1)0.05 (0.01 to 0.21)
Either screening question plus help question96 (86 to 99)4589 (87 to 91)7959.1 (7.4 to 11.1)0.05 (0.012 to 0.19)
General practitioner diagnosis79 (65 to 88)3794 (92 to 95)83513 (9.6 to 17.4)0.23 (0.13 to 0.39
  • Ideal method for all variables is composite international diagnostic interview.

  • * Compared with 47 true positive responses in composite international diagnostic interview.

  • † Compared with 889 true negative responses in composite international diagnostic interview.