Table

Baseline clinical and laboratory characteristics before treatment for patients with cerebral malaria for both treatment arms. Values are means with standard deviations unless otherwise indicated

VariableArtemether (n=51)Quinine (n=52)
Age in months28.0 (14.6)26 (16.4)
Weight in kg11.0 (2.8)10.8 (2.4)
Temperature in degrees Celsius38.3 (1.3)38.9 (8.9)
Coma duration in hours11.8 (9.6)11.3 (10.3)
Systolic blood pressure in mm Hg89.2 (12.7)91.0 (11.9)
Diastolic blood pressure in mm Hg62.0 (11.4)61.0(13.7)
Haemoglobin in mmol/l1.0 (0.3)0.9 (0.4)
Alanine amino transferase (ALT) in IU/l31.8 (44.2)85.0 (40.0)
Aspartate amino transferase (AST) IU/l70.7 (67.4)166.0 (70.8)
Total bilirubin in μmol/l22.7 (17.1)29 (37.6)
Creatinine in μmol/l8.84 (5.5)7.96 (2.7)
Potassium in mmol/l4.6 (0.77)4.2 (0.85)
White blood cells x106/l9614 (6469)9347 (5029)
Median parasite density per μl (interquartile range)84 474 (16 622-208 010)75 526 (13 145-324 600)