Table 1

Characteristics of the 12 available trials of treatment based on folic acid

Median pretreatment concentration
ReportNo of patientsMean age (years)Treatment duration (weeks)Homocysteine (╬╝mol/l)Folate (nmol/l)
Brattstr├Âm165365614.313.0
Den Heijer I175256817.29.7
Den Heijer II1717853811.912.7
Den Heijer III179261813.612.1
Ubbink I189139624.94.7
Ubbink II192640620.64.7
Naurath2028575312.49.7
Pietrzik I217025127.423.1
Pietrzik II211282547.521.3
Woodside221124089.89.2
Cuskelly231723125.66.4
Saltzman241058414.419.9
Total111452611.811.6