Table 2

Relative risks (95% confidence intervals) for coronary heart disease by birth weight in women who were singletons and had been born full term

Birth weight (g)
<2268>2268-2495>2495-3175>3175-3856>3856-4536>4536z for trend (P value)
All non-fatal coronary heart disease*;
No of cases Relative risk:245027241310921
Age adjusted1.361.220.99Referent0.970.75-1.58 (0.112)
Multivariate1.32 (0.87 to 1.99)1.15 (0.85 to 1.54)1.02 (0.88 to 1.19)Referent0.92 (0.75 to 1.14)0.68 (0.44 to 1.06)-2.10 (0.036)
Non-fatal myocardial infarction
No of cases15271632627013
Multivariate relative risk1.29 (0.77 to 2.18)0.95 (0.64 to 1.42)0.92 (0.71 to 1.20)Referent0.92 (0.71 to 1.20)0.66 (0.38 to 1.15)-0.84 (0.401)
Coronary revascularisation
No of cases13371642246014
Multivariate relative risk1.32 (0.75 to 2.31)1.61 (1.13 to 2.28)1.14 (0.93 to 1.40)Referent0.94 (0.71 to 1.25)0.85 (0.50 to 1.47)-2.71 (0.006)
  • *Non-fatal myocardial infarction or coronary revascularisation. Total end point considers only the first event, so the sum of the separate end points is greater than the number of total coronary heart disease events.

  • †Adjusted for age (continuous) and time period.

  • ‡Further adjusted for body mass index (tenths), cigarette smoking (never; past; current: 1-14, 15-24, ≥25 cigarettes/day, quantity unknown, missing data), reported hypertension, reported raised cholesterol concentration, parental history of myocardial infarction under 60, diabetes, menopausal status (premenopausal, postmenopausal, dubious, missing data), and use of postmenopausal hormones (premenopausal, never use, past use, current use, missing data).