Table 2

 Weight loss (crude and imputed if missing), body mass index reduction, and physical activity change at programme end and one year follow-up. Values are means (95% CI)

Weight WatchersSlimming WorldRosemary ConleySize DownGeneral practicePharmacyChoiceExercise/comparator
Weight loss at programme end (kg)
BOCF†4.43 (3.6 to 5.3)**3.56 (2.7 to 4.4)**4.23 (3.2 to 5.2)**2.38 (1.7 to 3.1)**1.37 (0.4 to 2.3)*2.11 (1.0 to 3.2)**3.32 (2.5 to 4.1)**2.01 (1.2 to 2.8)**
Complete cases only‡5.15 (4.2 to 6.1)**4.25 (3.3 to 5.2)**5.29 (4.2 to 6.4)**3.22 (2.3 to 4.1)**2.17 (0.7 to 3.7)*2.80 (1.4 to 4.2)**3.81 (2.9 to 4.7)2.96 (1.8 to 4.1)**
LOCF‡4.71 (3.9 to 5.6)**3.76 (2.9 to 4.6)**4.37 (3.4 to 5.4)**2.37 (1.7 to 3.1)**1.13 (0.0 to 2.3)2.14(1.0 to 3.2,)**3.56 (2.8 to 4.3)**1.87 (1.0 to 2.78)**
Physical activity change to programme end (kcal/week)
BOCF†1926 (1225 to 2629)**1899 (1226 to 2571)**1801 (1155 to 2447)**1480 (701 to 2259)**1895 (963 to 2826)**2720 (1790 to 3649)**1986 (1245 to 2727)**1608, (988 to 2228)**
Complete cases only‡1946 (1238 to 2654)**1957 (1267 to 2648)**1856 (1193 to 2520)**1542 (733 to 2351)**1980 (1010 to 2949)**2885 (1912 to 3857)**2159 (1362 to 2955)**1747 (1080 to 2415)**
Change in physical activity to programme end (minutes/week)§
Moderate and vigorous58 (42 to 75)60 (42 to 79)49 (33 to 65)55 (35 to 75)47 (25 to 70)73 (51 to 94)59 (40 to 77)51 (36 to 67)
Walking7 (−6 to 19)1 (−12 to 13)14 (2 to 26)16 (3 to 29)12 (−4 to 28)1 (−11 to 14)5 (−6 to 17)7 (−3 to 18)
Weight loss at one year
BOCF†3.46 (2.1 to 4.8)**1.89 (0.9 to 2.9)**2.12 (0.9 to 3.4)**2.45 (1.3 to 3.6)**0.83 (−0.4 to 2.0)0.66 (−0.4 to 1.7)2.15 (0.9 to 3.4)**1.08 (0.1 to 2.1)*
Complete cases only‡4.43 (2.7 to 6.1)**3.10 (1.5 to 4.7)**3.27 (1.4 to 5.1)**3.71 (2.0 to 5.4)**1.26 (−0.6 to 3.1)1.19 (−0.7 to 3.1)2.94 (1.2 to 4.7)**1.66 (0.1 to 3.2)*
LOCF‡4.35 (3.0 to 5.7)**3.28 (2.2 to 4.4)**3.17 (1.8 to 4.5)**3.10 (1.9 to 4.3)**1.13 (−0.1 to 2.4)1.85 (0.5 to 3.2)*2.96 (1.7 to 4.3)**1.33 (0.2 to 2.4)*
Physical activity change to one year (kcal/week)
BOCF†2048 (1262 to 2834)**1362 (645 to 2078)**1429 (657 to 2202)**1429 (644 to 2213)**861 (256 to 1467)*1473 (742 to 2203)**1642 (837 to 2448)**1766 (1044 to 2487)**
Complete cases only‡2069 (1276 to 2861)**1404 (666 to 2141)**1473 (678 to 2268)**1488 (673 to 2303)**861 (256 to 1467)*1562 (792 to 2332)**1659 (846 to 2472)**1899 (1129 to 2668)**
Change in physical activity to one year (minutes/week)§
Moderate and vigorous60 (40 to 79)21 (3 to 39)25 (10 to 40)19 (4 to 33)14 (−6 to 35)27 (3 to 51)32 (14 to 50)42 (25 to 60)
Walking−2 (−15 to 12)−9 (−22 to 4)−3 (−8 to 13)7 (−7 to 21)−12 (−26 to 3)17 (−0.4 to 34)−2 (−14 to 9)−3 (−14 to 8)
Body mass index reduction at one year (kg/m2)
BOCF†1.17 (0.7 to 1.7)**0.71 (0.4 to 1.0)**0.75 (0.3 to 1.1)**0.67 (0.3 to 1.0)**0.32 (−0.1 to 0.7)0.31 (0.0 to 0.7)0.90 (0.5 to 1.3)**0.45 (0.1 to 0.8)*
Complete cases only‡1.8 (1.1 to 2.5)**1.36 (0.7 to 2.0)**1.33 (−0.6 to 2.0)**1.19 (0.5 to 1.8)**0.66 (−0.1 to 1.4)0.73 (−0.1 to 1.6)1.42 (0.8 to 2.1)**0.79 (0.2 to 1.4)*

BOCF=baseline observation carried forward; LOCF=last observation carried forward.

*P<0.05 (paired t test from baseline).

**P≤0.001 (paired t test from baseline).

†Primary analysis.

‡Sensitivity analyses.

§Change from baseline in minutes/week using baseline observation carried forward.