Table 6

 Comparison of QRISK and Anderson Framingham risk equation in classification of female patients’ 10 year risk of cardiovascular disease (low (<10%), intermediate (10% to <20%), high (≥20%)) and observed and predicted risk

Anderson FraminghamQRISKTotal No (%) of patients reclassified
Low riskIntermediate riskHigh risk
Low risk
No of patients384 92310 90168711 588 (2.1)
No of cardiovascular events5 5891 140106
% of patients classified70.92.00.3
Average predicted risk of cardiovascular event (%):
 QRISK2.712.723.2
 Anderson Framingham3.88.48.4
Observed risk % (95% CI)3.1 (3.0 to 3.2)18.6 (17.3 to 20.0)29.0 (22.7 to 36.7)
Intermediate risk
No of patients48 72961 92510 01058 739 (10.8)
No of cardiovascular events1 9434 8141 340
% of patients classified9.011.41.8
Average predicted risk of cardiovascular event (%):
 QRISK7.514.023.9
 Anderson Framingham12.514.415.6
Observed risk % (95% CI)7.5 (7.0 to 7.9)14.1 (13.6 to 14.6)22.7 (21.2 to 24.3)
High risk
No of patients94012 62612 24613 566 (2.5)
No of cardiovascular events731 2511 771
% of patients classified0.22.32.3
Average predicted risk of cardiovascular event (%):
 QRISK8.515.825.9
 Anderson Framingham22.824.028.0
Observed risk % (95% CI)15.4 (10.9 to 21.3)16.9 (15.8 to 18.1)24.2 (22.9 to 25.6)